Tolpi-150 is a prescription medication widely used to manage neuropathic pain and seizures. It is part of the antiepileptic and neuropathic pain management category, providing relief for conditions such as epilepsy, nerve pain, and fibromyalgia.

Composition:
Each tablet contains:

Topiramate 150 mg ? An antiepileptic drug that helps control abnormal electrical activity in the brain.

Uses and Indications:

Partial and generalized seizures in adults and children.

Prevention of migraine headaches.

Management of neuropathic pain associated with conditions like diabetic neuropathy.

Mechanism of Action:
Topiramate stabilizes neuronal membranes by enhancing GABA activity and inhibiting excitatory neurotransmitters. This reduces excessive electrical activity in the brain, controlling seizures and mitigating nerve pain signals.

Dosage and Administration:
The usual adult dose is 150 mg daily, administered in divided doses. Dose adjustment is necessary based on individual response, kidney function, and tolerance. Gradual titration is recommended to minimize side effects.

Precautions:

Adequate hydration is important to prevent kidney stone formation.

Patients with liver or kidney disease should use with caution.

Regular monitoring of blood parameters is recommended during prolonged use.

Side Effects:

Dizziness, drowsiness, or coordination issues.

Weight loss or decreased appetite.

Tingling sensations in hands or feet.

Rarely, cognitive impairment or mood changes.